Persona 5 [NPEB02436]

[Annie]

How do I go about making this game run with at least 15 fps with an AMD FX 8350, 16 Gbs of Ram and a GTX 980 Ti? What are the optimal settings? And I believe AMD does not support hyper threading?

That CPU is garbage, your FPS will be low.
Try running RPCS3.exe and then setting core affinity on 0 2 4 6 on task manager. Switch between SPU Interpreter / SPU Recompiler to see how it differs in performance. Always use PPU Recompiler though.
In config.yml you may want to try to set Preferred SPU threads to 1/2/3 and SPU pooling to true.